科

研

项

目

1、北京市自然科学基金项目，基于AhR-Caspase探究黑米花色苷及其主要代谢物减轻杂环胺毒性的分子机制，主持

2、企事业单位委托项目，杂粮超微粉碎及其饮料产品相关指标分析，主持

3、北京市属高校青年拔尖人才培育计划项目，黄酮类化合物对食品中杂环胺PhIP生成和毒性的抑制机制研究，主持

4、国家自然科学基金项目，鹿茸蛋白模拟胃肠消化物中活性成分肠吸收及免疫调节机理研究，主持

5、北京市教委科研计划项目，糖单酯的酶法合成及其抗菌机理的研究，主持

论文发表

1. Zhang Mingxin, Zhou Na, Zhao Lei*, Zhao Liang*. Black rice anthocyanins nanoparticles based on bovine serum albumin and hyaluronic acid: Preparation, characterization, absorption and intestinal barrier function protection in Caco-2 monolayers. International Journal of Biological Macromolecules, 2024, 267: 131325.

2. Zhang Mingxin, Wang Ou, Cai Shengbao, Zhao Lei*, Zhao Liang*. Composition, functional properties, health benefits and applications of oilseed proteins: A systematic review. Food Research International, 2023, 171: 113061.

3. Ai Xin#, Pan Fei#, Yang Zichen, Li Jiayi, Tuersuntuoheti Tuohetisayipu, Wang Ou, Zhao Lei*, Zhao Liang*. Computational design of a chitosan derivative for improving the color stability of anthocyanins: Theoretical calculation and experimental verification. International Journal of Biological Macromolecules, 2022, 219: 721-729.

4. Pan Fei, Zhao Lei*, Cai Shengbao, Tang Xiaoning, Mehmood Arshad, Alnadari Fawze, Tuersuntuoheti Tuohetisayipu, Zhou Na, Ai Xin. Prediction and evaluation of the 3D structure of Macadamia integrifolia antimicrobial protein 2 (MiAMP2) and its interaction with palmitoleic acid or oleic acid: An integrated computational approach. Food Chemistry, 2022, 367: 130677.

5. Zhao Lei*, Zhou Na, Zhang Huimin, Pan Fei, Ai Xin, Wang Yong, Hao Shuai, Wang Chengtao. Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways. Food and Chemical Toxicology, 2021, 157: 112582.

6. Zhao Lei*, Pan Fei, Mehmood Arshad, Zhang Huimin, Rehman Ashfaq Ur, Li Jiayi, Hao Shuai, Wang Chengtao*. Improved color stability of anthocyanins in the presence of ascorbic acid with the combination of rosmarinic acid and xanthan gum. Food Chemistry, 2021, 351: 129317.

7. Mehmood Arshad, Zhao Lei*, Wang Yong, Pan Fei, Hao Shuai, Zhang Huimin, Iftikhar Asra, Usman Muhammad. Dietary anthocyanins as potential natural modulators for the prevention and treatment of non-alcoholic fatty liver disease: A comprehensive review. Food Research International, 2021, 142: 110180.

8. Mehmood Arshad, Zhao Lei*, Chengtao Wang*, Nadeem Muhammad, Raza Ali, Ali Nawazish, Shah Amjad Abbas. Management of hyperuricemia through dietary polyphenols as a natural medicament: A comprehensive review. Critical Reviews in Food Science and Nutrition, 2019, 59(9): 1433-1455.

9. Zhao Lei, Yang Huaqing, Xu Meili, Wang Xin, Wang Chengtao*, Lian Yunhe*. Stevia residue extract ameliorates oxidative stress in D-galactose-induced aging mice via Akt/Nrf2/HO-1 pathway. Journal of Functional Foods, 2019, 52: 587-595.

10. Zhao Lei*, Zhang Yali, Liu Guorong, Hao Shuai, Wang Chengtao*, Wang Yong. Black rice anthocyanin-rich extract and rosmarinic acid, alone and in combination, protect against DSS-induced colitis in mice. Food & Function, 2018, 9(5): 2796-2808.

授权专利

1、赵磊, 潘飞, 王成涛. 一种补铁花色苷蓝色素及其制备方法和应用. CN202010529630.3

2、赵磊, 王成涛, 李煜彬. 一种腌肉料及其制备方法和应用. CN201811604221.4

3、徐美利, 赵磊, 杨香瑜, 安晓东, 李乾丽, 连运河, 王成涛. 一种甜叶菊酚类提取物及其在降血脂制品中的应用. CN201610745204.7

4、徐美利, 赵磊, 杨香瑜, 安晓东, 李乾丽, 连运河, 王成涛. 一种甜叶菊酚类提取物及其在抗炎制品中的应用. CN201610745221.0

5、田文礼, 彭文君, 潘飞, 刘栋梁, 赵磊, 赵亮, 方小明, 李相昕, 陈华磊. 一种高活性α-糖苷酶抑制肽的快速筛选方法及其应用. CN202311485221.8

著作

1. 赵磊. 甜叶菊资源综合开发与高值化利用. 化学工业出版社, 2021.

获奖情况