尹胜

1983年7月

硕导

yinsheng@btbu.edu.cn

个人简历

教育经历:

2002-2006,中国农业大学食品科学与营养工程学院,生物工程专业,学士

2006-2011,中国农业大学食品科学与营养工程学院,食品科学专业,博士

工作经历:

2011- 2012,比利时布鲁塞尔自由大学工业微生物与食品生物技术实验室,博士后

2013-2015,太阳成集团tyc122cc,讲师

2015至今,太阳成集团tyc122cc,副教授

主讲课程

本科生:《特殊食品概论》、《功能性食品》、《食品安全学》

研究生:《基因工程原理与应用》、《食品生物技术进展》、《现代微生物与发酵工程》

主要研究领域

1、食品与营养健康价值产物的合成生物制造

2、微生物代谢产物的生物合成与调控

3、微生物资源(发酵微生物、益生菌等)开发与应用

主要学术成果(课题、论文、获奖、专利等)

承担的主要科研项目(限10项):

1、中国乳制品工业协会乳业科技创新基金-蒙牛专项“格氏乳杆菌的粘蛋白降解机制及相关益生菌的筛选”(2023-2024)。

2、北京市自然基金委-市教委联合资助项目“酿酒酵母中高级醇合成关键酶系的鉴定及其途径特异性表达调控研究”(2019-2022)。

3、国家自然科学基金青年科学基金“基于蛋白组学的紫红曲霉中红曲色素生物合成分子机制研究”(2015-2017)。

4、北京市自然科学基金青年科学基金“天冬氨酸半醛脱氢酶为筛选标记的新型乳酸菌食品级载体构建技术的研究”(2015-2017)。

发表的代表性论文(限10篇):

1. Yin Sheng*, Li Yujie, Hou Jialing. Expression of the two-component regulator StyS/StyR enhanced transcription of the styrene monooxygenase gene styAB and indigo biosynthesis in Escherichia coli. Enzyme and Microbial Technology, 2024, 174, 110381.

2. Du Lingyan, Yue Jianming, Zhu Yiying, Yin Sheng*. Production of indigo by recombinant Escherichia coli with expression of monooxygenase, tryptophanase, and molecular chaperone. Foods, 2022, 11 (14), 2117.

3. Yin Sheng*, Zhu Yiying, Zhang Bin, Huang Baozhu, Jia Ru. Diverse effects of amino acids on Monascus pigments biosynthesis in Monascus purpureus. Frontiers in Microbiology, 2022, 13, 951266.

4. Yin Sheng*, Yang Dongmei, Zhu Yiying, Huang Baozhu. Methionine and S-adenosylmethionine regulate Monascus pigments biosynthesis in Monascus purpureus. Frontiers in Microbiology, 2022, 13, 921540.

5. Wang Hui, Li Yujie, Che Yixin, Yang Dongmei, Wang Qi, Yang Huaqing, Julien Boutet, Robert Huet, Yin Sheng*. Production of L-methionine from 3-methylthiopropionaldehyde and O-acetylhomoserine by catalysis of the yeast O-acetylhomoserine sulfhydrylase. Journal of Agricultural and Food Chemistry, 2021, 69 (28), 7932-7937.

6. Che Yixin, Yin Sheng*, Wang Hui, Yang Huaqing, Xu Ruixin, Wang Qi, Wu Yiping, Julien Boutet, Robert Huet, Wang Chengtao*. Production of methionol from 3-methylthiopropionaldehyde by catalysis of the yeast alcohol dehydrogenase Adh4p. Journal of Agricultural and Food Chemistry, 2020, 68, 4650-4656.

7. Wu Yiping, Zha Musu, Yin Sheng*, Yang Huaqing, Julien Boutet, Robert Huet, Wang Chengtao*, Sun Baoguo. Novel method for L-methionine production catalyzed by the aminotransferase ARO8 from Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry, 2018, 66, 6116-6122.

8. Zha Musu, Sun Baoguo, Yin Sheng*, Arshad Mehmood, Cheng Lei, Wang Chengtao*. Generation of 2-furfurylthiol by carbon-sulfur lyase from the Baijiu yeast Saccharomyces cerevisiae G20. Journal of Agricultural and Food Chemistry, 2018, 66 (9), 2114-2120.

9. Zha Musu, Yin Sheng*, Sun Baoguo, Wang Xin, Wang Chengtao*. STR3 and CYS3 contribute to 2-furfurylthiol biosynthesis in Chinese sesame-flavored Baijiu yeast. Journal of Agricultural and Food Chemistry, 2017, 65 (27), 5503-5511.

10. Yin Sheng, Lang Tiandan, Xiao Xiao, Liu Li, Sun Baoguo, Wang Chengtao*. Significant enhancement of methionol production by co-expression of the aminotransferase gene ARO8 and the decarboxylase gene ARO10 in Saccharomyces cerevisiae. FEMS Microbiology Letters, 2015, 362 (5), fnu043.

代表性的专利(限10篇):

1. 一种提高紫红曲霉中黄色素和橙色素合成的发酵方法. 2023, 专利授权号ZL202210815142.8

2. 一种改变紫红曲霉中红曲色素合成代谢模式并提高合成量的发酵方法. 2023, 专利授权号ZL202210816447.0

3. 一种提高紫红曲霉中红曲色素合成的发酵方法. 2021, 专利授权号ZL202010034962.4

4. 一种可双向调节紫红曲霉中红曲色素合成量的发酵方法. 2021, 专利授权号ZL202010034963.9


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